Sandostatin® (octreotide acetate)
Sandostatin® (octreotide acetate)
Sandostatin® LAR Depot (octreotide acetate) is an injectable suspension treatment indicated for patients with Acromegaly, Carcinoid Tumors and diarrhea related to Vasoactive Intestinal Peptide Tumors.
It works by binding to somatostatin receptors in the body, reducing the release of overactive peptide hormones such as human growth hormone as seen in Acromegaly and the multiple GI peptides associated with Carcinoid tumors and VIPomas.
Long-term treatment of the profuse watery diarrhea associated with VIP-secreting tumors in patients with carcinoid syndrome and VIPomas. It also helps with the treatment of the severe diarrhea and flushing episodes associated with metastatic carcinoid tumors and patients with acromegaly who have had inadequate response to surgery and/or radiotherapy or for whom surgery and/or radiotherapy is not an option (the goal of treatment in acromegaly is to reduce GH and IGF-1 levels to normal).
Administration Information
SANDOSTATIN LAR DEPOT 10 mg, 20 mg, and 30 mg is indicated in patients in whom initial treatment with Sandostatin Injection has been shown to be effective and tolerated.
It should be administered intramuscularly (IM) in the gluteal region in 4 week intervals and dosage is determined by the patient's diagnosis and prescribing physician.
Acromegaly: 20 mg every 4 weeks for 3 months
Carcinoid Tumors and VIPomas: 20 mg every 4 weeks for 2 months
Renal Impairment, Patients on Dialysis: 10 mg every 4 weeks
Hepatic Impairment, Patients With Cirrhosis: 10 mg every 4 weeks
Potential Side Effects
The most common side effects of SANDOSTATIN LAR DEPOT are:
Gallbladder abnormalities (stones/sludge)
Cholelithiasis
Abdominal pain
Diarrhea
Nausea
Constipation
Flatulence
Headache
Back pain
Tell your doctor about any side effect that bothers you or that does not go away. These are not all the possible side effects of SANDOSTATIN LAR DEPOT. For more information, ask your doctor or pharmacist. Please see Full Prescribing Information,
Helpful Resources
What is SANDOSTATIN LAR DEPOT?
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