Tyruko
Tyruko
TYRUKO® (natalizumab-sztn), the first FDA-approved biosimilar to TYSABRI® (natalizumab), a prescription medication used to treat relapsing forms of Multiple Sclerosis (MS) and moderately to severely active Crohn's Disease.
It is shown to help control relapses of MS and acts as an integrin receptor antagonist to prevent immune cells from entering the brain and spinal cord, It is also shown to work as an anti-inflammatory monoclonal antibody to induce remission in Crohn’s disease by blocking immune cells from entering the gut.
It carries a risk of PML (progressive multifocal leukoencephalopathy) requiring a strict REMS program for patient monitoring.
Administration Information
TYRUKO is administered as an intravenous or "IV" infusion every 4 weeks.
Potential Side Effects
Most common side effects
The most common side effects of TYRUKO include:
headache
lung infection
vaginitis
stomach-area pain
feeling tired
depression
rash
urinary tract infection
pain in your arms and legs
nose and throat infections
joint pain
diarrhea
nausea
Tell your doctor about any side effect that bothers you or that does not go away. These are not all the possible side effects of TYRUKO. Ask your doctor for more information.
Helpful Resources
What is TYRUKO?
What is a biosimilar?
Sandoz One Source Patient Support Program
Patient Resources
Sage Infusion MS Tips
Sage Infusion Crohn's Tips
Before you attend your first appointment at Sage Infusion, please make sure to review the documents below. The Patient Consent Form and HIPAA Privacy Authorization Form need to be filled out and signed ahead of your appointment, whereas the Notice of Privacy Practices, Patient Rights and Responsibilities, and Appointment Lateness and Cancelation are for reference only. Please contact us if you have any questions!
Patient Consent Form
HIPAA Privacy Authorization Form
Notice of Privacy Practices
Patient Rights and Responsibilities
Appointment Lateness and Cancelation
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