Tepezza

Tepezza

Tepezza (teprotumumab-trbw) is a drug used for the treatment of thyroid eye disease.

Tepezza (teprotumumab-trbw) is a drug used for the treatment of thyroid eye disease.

Thyroid eye disease is a rare, autoimmune disease characterized by proptosis (a condition where the eyes are pushed forward and bulge outward) leading to eye pain, double vision and difficulty closing the eyelid.

Tepezza reduces eye bulging and double vision. It also improves the signs and symptoms of Thyroid Eye Disease (TED), including eye pain, redness, and swelling.

In clinical trials: more than 8 out of 10 patients taking Tepezza experienced visible reduction in eye swelling; 7 out of 10 patients saw improvement in double vision; and 5 out of 10 patients saw their double vision completely go away.

Resources

Administration Information

Tepezza is administered as an intravenous infusion once every three weeks for a total of eight infusions. It takes about 60-90 minutes to receive the infusion. An observation time of 30-60 minutes may be required after your infusion.

8
Total Infusions
1
Infusion Every 3 Weeks
1hr
60-90 minute Infusions
1hr
Up to 1 Hour Observation

Potential Side Effects

The most common side effects of Tepezza are muscle spasm, nausea, hair loss, diarrhea, fatigue, high blood sugar, dry skin, change in taste, and headache.

Tepezza may cause serious side effects including infusion reactions, worsening of inflammatory bowel disease, and high blood sugar.

Before starting treatment with Tepezza, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for blood sugar control as prescribed by your doctor.

Tepezza should not be used during pregnancy. Women of child bearing age should use effective birth control (contraception) before you start Tepezza, while you’re being treated, and for at least 6 months after the final dose of Tepezza. A pregnancy test before you start Tepezza.

If you have inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis, Tepezza may make your IBD symptoms worse. If you have IBD, your doctor may want to make sure it’s under control before you start treatment.

For a full list of potential side effects, please see the Important Safety Information and Medication Guide on the Tepezza website.

Helpful Resources

EDUCATIONAL BROCHURE

HOW TEPEZZA CAN HELP THYROID EYE DISEASE

TEPEZZA COST SAVINGS AND SUPPORT

SAGE PATIENT STORIES

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